Mark J. Holterman, Medical

A Look at Some Early Indicators of Autoimmunity


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A former National Merit Scholar at Yale University, Mark Holterman, MD leverages decades of clinical experience as a professor of surgery and pediatrics at the University of Illinois College of Medicine in Peoria, Illinois. Also a researcher, Dr. Mark Holterman holds a particular interest in regenerative medicine, stem cell therapies, obesity, innovative cancer treatments, and autoimmunity.

Autoimmunity refers to a condition in which the body’s immune system begins to attack the body itself. Some form of autoimmunity is present in everyone, but when serious it can lead to a range of autoimmune diseases that include type 1 diabetes, multiple sclerosis, and lupus. Although it is not known what causes autoimmune disease, genetic history, infections, diet, and chemical exposure are all thought to play a role.

Many autoimmune disorders have unique symptoms. However, the early symptoms are often quite similar. In addition to fatigue and muscle aches, individuals with autoimmune disorders may experience swelling, inflammation, and a fever. Hair loss, hand and foot numbness, and rashes on the skin may also be present. Lastly, autoimmune disorders often make it difficult for individuals to concentrate.

Mark J. Holterman, Medical

About the 2018 AACA Annual Meeting


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American Association of Clinical Anatomists

An accomplished pediatric surgeon with upwards of three decades of experience in the field, Mark Holterman, MD, serves as a faculty member at the University of Illinois College of Medicine. An active member of a number of professional organizations, Dr. Mark Holterman belongs to the American Association Of Clinical Anatomists (AACA).

The AACA will hold its 35th Annual conference on July 8-12, 2018 at the Grand Hyatt Buckhead in Atlanta, Georgia. Hosted by the Morehouse School of Medicine, the event will feature keynote speakers and breakout sessions geared toward arming attendees with the latest advances and information in the field of clinical anatomy.

Lodging for the conference will be available on-site at the Grand Hyatt and shuttle options will be available from the Hartsfield-Jackson International Airport to the hotel for those traveling by plane to the conference. To learn more about the meeting or register, visit

Community Outreach, Mark J. Holterman

IPSAC-VN Nonprofit Group Improves Pediatric Surgery In Vietnam


Mark J. Holterman, Medical

NIH Medical Scientist Training Program Funds Biomedical Research


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A professor of surgery and pediatrics at the University of Illinois College of Medicine, Dr. Mark Holterman formerly served as an attending pediatric surgeon at Rush University Medical Center and as the surgeon-in-chief at Advocate Children’s Hospital. Mark Holterman, MD, started his medical career at the University of Virginia in the National Institutes of Health Medical Scientist Training Program (MSTP).

Funded through the Ruth L. Kirschstein Grant, the MSTP program supports the training of qualified students who are seeking dual doctorates (MD and PhD) and are motivated to pursue biomedical research and other research-related careers in academia, industry, and government. Benefitting from an education that integrates biomedical sciences with clinical training, 900 trainees at 48 sites are funded through the MSTP program.

Students can choose research projects in a wide array of specialties, including biology, chemistry, behavioral science, and computer science. Those who prevail in the highly competitive grant selection process typically spend eight years obtaining their dual degrees. MSTP grant winners receive a stipend and tuition allowance.

Mark J. Holterman, Medical

ADA Praises Congress for Funding Special Diabetes Program


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American Diabetes Association

With three decades of experience as a physician and an educator, Mark Holterman, MD, serves as a professor of medicine at the University of Illinois College of Medicine. In addition to his work as an educator, Dr. Mark Holterman engages with such organizations as the American Diabetes Association (ADA).

The ADA recently praised the federal government for agreeing to fund the Special Diabetes Program (SDP) to the tune of $600 million. SDP is one of the major drivers of research into type 1 diabetes and how to prevent type 2 diabetes for American Indians across the country. Thanks to this new funding, researchers will be able to continue exploring new treatments for diabetes in these communities, which are at exceptionally high risk of developing the disease.

The ADA recognized the Diabetes Caucuses in both houses of Congress for their work in helping this funding package come to fruition. The organization says it will continue to work with lawmakers to ensure that programs such as SDP continue to receive the support they need.

Mark J. Holterman, Medical

Study – Enhanced Recovery Plan for Colorectal Surgical Patients


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Dr. Mark J. Holterman

Mark Holterman, MD, serves as a professor of surgery and pediatrics at the University of Illinois College of Medicine in Peoria. Dr. Mark Holterman also is a fellow of the American College of Surgeons.

According to a recent study published by the American College of Surgeons, a new procedure for handling patient care through every stage of colorectal surgery not only helps these individuals have better outcomes, but also reduces the amount of time they have to stay in the hospital after surgery and results in lowered opioid pain medication usage.

In their study, researchers found that this new enhanced recovery program reduced hospital stays by an average of two days. Patients also were 14 percent less likely to develop abnormal bowel function and required 500-plus fewer units of morphine to manage their pain. The study’s lead author, Ian Paquette, MD, FACS, touted the results as a major breakthrough for surgeons and patients looking for better ways to handle recovery.

Mark J. Holterman, Medical

AACA Looks at Parametric Human


American Association of Clinical Anatomists  pic
American Association of Clinical Anatomists

A board-certified pediatric surgeon, Mark Holterman, MD, serves as a professor of surgery and pediatrics at the University of Illinois College of Medicine in Peoria. Active in the medical field outside of his work, Dr. Mark Holterman is a member of the American Association of Clinical Anatomists (AACA).

The AACA recently highlighted the work of a multidisciplinary team of doctors and data scientists that could fundamentally shift the way we doctors tailor individualized medical treatment. Dubbed the parametric human, researchers are close to developing a completely 3D-printable “virtual” human that can be customized with all the different musculoskeletal variations currently known.

Doctors would then be able to run diagnostic tests on this virtual human to potentially see how it can respond to certain types of treatment, eliminating the need for animal testing altogether. The group behind the project says the goal is to become intimately familiar with the human body, beyond the superficial diagrams and other data that is so often used in anatomical education.