Mark J. Holterman, Medical

About Mesenchymal Stem Cells


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Mark Holterman, MD, teaches coursework in surgery and pediatrics as a professor at the University of Illinois College of Medicine at Peoria. An expert in cellular and regenerative therapies, Dr. Mark Holterman also helped to found the Alliance for the Advancement of Cellular Therapies and the Sunshine Foundation.

A charitable organization, the Sunshine Foundation was created to support cellular and regenerative therapies. It was inspired by three young individuals who received effective cellular and regenerative therapies. Celltex Therapeutics, a biotechnology firm, provided regenerative therapy for one of the individuals to treat systemic juvenile idiopathic arthritis and dysautonomia.

Celltex utilizes stem cells known as mesenchymal stem cells when conducting cellular therapy. Mesenchymal stem cells, also known as MSCs, can be readily found in tissue throughout the human body. Fat tissue is a plentiful source for MSCs, but they are often taken from bone marrow, umbilical cord blood, and placenta tissue as well.

MSCs have the ability to grow into many different cell types, such as bone and muscle, and play a role in combating inflammation, improving healing, stopping cellular decay, and forming new blood vessels. For additional information, visit